Mary Whipple, PhD, RN, PHN

Assistant Professor
Mary Whipple


Office Address

6-152 Weaver Densford
308 Harvard Street SE
Minneapolis, MN 55455
United States


Assistant Professor


PhD, University of Minnesota School of Nursing (Major: Nursing, Minor: Gerontology)

BSN, University of Minnesota School of Nursing (Major: Nursing)

BA, Luther College (Major: Biology and Psychology)


Postdoctoral Fellowship, Division of Geriatric Medicine, University of Colorado School of Medicine

Licensures and Certifications

Registered Nurse, MN Board of Nursing
Public Health Nurse, MN Board of Nursing
Registered Nurse, CO Board of Nursing

Expand all


Research Summary:

Dr. Whipple’s research focuses on understanding the effects of sedentary behavior and physical activity on cardiovascular health among older adults, with a particular focus on individuals with type 2 diabetes and peripheral artery disease. Her primary goal is to understand both the causes and consequences of sedentary behavior to help older adults develop strategies to manage their chronic conditions and improve/preserve their physical function and quality of life.

Academic Interests and Focus:

Sedentary Behavior, Physical Activity; Cardiovascular Disease; Diabetes; Gerontology; Women's Health; Sex and Gender Differences; Nursing Research; Grant Writing and Development

Professional Memberships:

Society for Vascular Nursing
Society for Vascular Medicine
Midwest Nursing Research Society
American Heart Association
Gerontological Society of America
Sigma Theta Tau International

Selected Grants

Title: Prolonged Sedentary Behavior in Older Women with Type 2 Diabetes: A Program of Research to Understand Knowledge, Engagement, and Relationship to Cardiometabolic Risk
Funding Source: Loan Repayment Program, National Institute of Nursing Research, National Institutes of Health (L30NRO19425)
Principal Investigator: Whipple, Mary Olivia
Project Period: 07/01/2020 - 06/30/2022

Title: Understanding the Role of Knowledge, Mood, and Sense of Meaning in Sedentary Behavior Engagement Among Older Women with Type 2 Diabetes
Funding Source: Ludeman Family Center for Women's Health Research Junior Faculty Research Development Award, University of Colorado Anschultz Medical Campus
Principal Investigator: Whipple, Mary Olivia
Project Period: 09/01/2020 - 12/31/2021

Title: Relationship Between Sedentary Behavior, Glucose Tolerance, and Microvascular Function in older Women with Type 2 Diabetes
Funding Source: Small Grants Program, Division of General Internal Medicine, School of Medicine, University of Colorado Anschutz Medical Campus
Principal Investigator: Whipple, Mary Olivia
Project Period: 12/01/2019 - 11/30/2021

Title: Physiologic Effects of Prolonged Sedentary Bouts Among Older Women with and without Type 2 Diabetes
Funding Source: Integrative Physiology of Aging T32, Division of Geriatric Medicine, School of Medicine, University of Colorado Anschutz Medical Campus Funded through National Institute of Aging, National Institutes of Health (T32AG000279)
Principal Investigator: Robert Schwartz
Project Period: 09/01/2019 - 08/31/2021
Role: Postdoctoral Fellow

Title: Role of Diabetes and Sedentary Time in Outcomes of Structured Exercise Therapy for Peripheral Artery Disease
Funding Source: NIH NINR Natl Inst of Nursing
Principal Investigator: Whipple, Mary Olivia
Award Dates: 2017 - 2019

Title: Diabetes and Sedentary Time in Outcomes of Exercise in PAD
Funding Source: Midwest Nursing Research Society
Principal Investigator: Whipple, Mary Olivia
Award Dates: 2017 - 2019

Title: Barriers to Physical Activity and Association with Geriatric Syndromes in Older Adults with Peripheral Artery Disease 
Principal Investigator: Whipple, Mary Olivia
Funding Source: Nat'l Hartford Center for Gerontological Nursing Excel
Award Dates: 2015 - 2018

Selected Publications

Whipple MO, Pinto AJ, Abushamat LA, Bergouignan A, Chapman K, Huebschmann AG, Masters KS, Nadeau KJ, Scalzo RL, Schauer IE, Rafferty D, Reusch JEB, Regensteiner JG. (In press). Sex differences in physical activity among individuals with type 2 diabetes across the lifespan: A systematic review and meta-analysis. Diabetes Care.

Ranum RM, Toussaint LL, Whipple MO, Vincent A. (2022). Predictive bidirectional relationships between pain, fatigue, and dyscognition in fibromyalgia. Mayo Clinic Proceedings: Innovations, Quality and Outcomes, 6(2), 143–147. doi: 10.1016/j.mayocpiqo.2021.12.007

Whipple MO, Masters KS, Huebschmann AG, Scalzo RL, Reusch JEB, Bergouignan A, Regensteiner JG (2021). Acute effects of sedentary breaks on vascular health in adults at risk for type 2 diabetes: A systematic review. Vascular Medicine, 26(4), 448-458. doi: 10.1177/1358863X211009307. PMCID: PMC9074004

Scalzo RL, Schauer IE, Rafferty D, Knaub LA, Kvaratskhelia N, Johnson K, Pott GB, Abushamat LA, Whipple MO, Huebschmann AG, Cree-Green M, Reusch JEB, Regensteiner JG (2022). Single-leg exercise training augments in vivo skeletal muscle oxidative flux via greater vascular content and function in adults with type 2 diabetes. The Journal of Physiology, 600(4), 963-978. doi: 10.1113/JP280603. PMCID: PMC9006339

Whipple MO, Schorr EN, Talley KMC, Lindquist R, Wolfson J, Bronas UG, Treat-Jacobson D (2021). Individual differences in response to supervised exercise therapy for peripheral artery disease. Western Journal of Nursing Research, 43(8), 770-784 doi: 10.1177/0193945920977479. PMCID: PMC8209120.

Whipple MO, Regensteiner JG, Bergouignan A (2021). Is being physically active enough to be metabolically healthy?: The key role of sedentary behavior. Diabetes Care, 44(1), 17-19. doi: 10.2337/dci20-0064. PMCID: PMC8441549.

Whipple MO, Schorr EN, Talley KMC, Wolfson J, Lindquist R, Bronas UG, Treat-Jacobson D (2020). Influence of changes in sedentary time on outcomes of supervised exercise therapy in individuals with comorbid peripheral artery disease and type 2 diabetes. Annals of Vascular Surgery, 68, 369-383. doi: 10.1016/j.avsg.2020.03.040. PMCID: PMC7529715.

Whipple MO, Schorr E, Talley KMC, Lindquist R, Bronas UG, Treat-Jacobson, D (2019). A mixed methods study of perceived barriers to physical activity, geriatric syndromes, and physical activity levels among older adults with peripheral artery disease and diabetes. Journal of Vascular Nursing, 37(2), 91-105. doi: 10.1016/j.jvn.2019.02.001. PMCID: PMC6556121.

Salisbury D, Whipple MO, Burt M, Brown R, Mays R, Bakken M, Treat-Jacobson D (2019). Experience with implementing a structured exercise therapy program for peripheral artery disease. Journal of Clinical Exercise Physiology, 8(1), 1-12. doi: 10.31189/2165-6193-8.1.1. PMCID: PMC6529193.

Whipple MO, Schorr EN, Talley KMC, Lindquist R, Bronas UG, Treat-Jacobson D (2018). Variability in individual response to aerobic exercise interventions among older adults. Journal of Aging and Physical Activity, 26(4), 655-670. doi: 10.1123/japa.2017-0054. PMCID: PMC5871585.

Whipple MO, Hamel AV, Talley KMC (2018). Fear of falling among community-dwelling older adults: A scoping review to identify effective evidence-based interventions. Geriatric Nursing, 39, 170-177. doi: 10.1016/j.gerinurse.2017.08.005. PMCID: PMC5862787.

Salisbury DL, Whipple MO, Burt M, Brown R, Hirsch A, Foley C, Treat-Jacobson D (2018). Translation of an evidence-based therapeutic exercise program for patients with peripheral artery disease. Journal of Vascular Nursing, 36(1), 23-33. doi: 10.1016/j.jvn.2017.09.003. PMCID: PMC5862037.

Hoskin TL, Whipple MO, Nanda S, Vincent A (2018). Longitudinal stability of fibromyalgia symptom clusters. Arthritis Research and Therapy, 20(1), 37. doi: 10.1186/s13075-018-1532-0. PMCID: PMC5830338.

Vincent A, Whipple MO, Rhudy LM (2016). Fibromyalgia flares: A qualitative analysis. Pain Medicine, 17(3), 463-468. doi:10.1111/pme.12676.

Vij B, Whipple MO, Tepper S, Mohabbat A, Stillman M, Vincent A (2015). Frequency of migraine headaches in patients with fibromyalgia. Headache: The Journal of Head and Face Pain, 55(6), 860-865. doi:10.1111/head.12590.

Vincent A, Whipple MO, McAllister SJ, Aleman K, St. Sauver JL (2015). A cross-sectional assessment of the prevalence of multiple conditions and medication use in a sample of community-dwelling adults with fibromyalgia in Olmsted County, Minnesota. BMJ Open, 5(3), e006681. doi:10.1136/bmjopen-2014-006681. PMCID: PMC4360829.

Toussaint LL, Vincent A, McAllister SJ, Whipple MO (2015). Intra- and inter-patient symptom variability in fibromyalgia: Results of a 90-day assessment. Musculoskeletal Care, 13(2), 93-100. doi:10.1002/msc.1090.

Vincent A, Hoskin TL, Whipple MO, Clauw DJ, Barton DL, Benzo RP, Williams DA (2014). OMERACT-based fibromyalgia symptom subgroups: An exploratory cluster analysis. Arthritis Research and Therapy, 16(5), 463. doi:10.1186/s13075-014-0463-7. PMCID: PMC4221670.

Vincent A, Clauw DJ, Oh TH, Whipple MO, Toussaint LL (2014). Decreased physical activity attributable to higher body mass index influences fibromyalgia symptoms. PM&R, 6(9), 802-807. doi:10.1016/j.pmrj.2014.02.007.

Vincent A, Whipple MO, Oh TH, Guderian JA, Barton DL, Luedtke CA (2013). Early experience with a brief, multimodal, multidisciplinary treatment program for fibromyalgia. Pain Management Nursing, 14(4), 228-235. doi:10.1016/j.pmn.2011.05.001.

Vincent A, Benzo R, Whipple MO, McAllister SJ, Erwin PJ, Saligan L (2013). Beyond pain in fibromyalgia: Insights into the symptom of fatigue. Arthritis Research and Therapy, 15(6), 221. doi:10.1186/ar4395. PMCID: PMC3978642.

Whipple MO, McAllister SJ, Oh TH, Luedtke CA, Toussaint LL, Vincent A (2013). Construction of a US fibromyalgia registry using the fibromyalgia research survey criteria. Clinical and Translational Science, 6(5), 398-399. doi:10.1111/cts.12056. PMCID: PMC3801292.

Vincent A, Lahr BD, Wolfe F, Clauw DJ, Whipple MO, Oh TH, Barton DL, St. Sauver JL (2013). Prevalence of fibromyalgia: A population-based study in Olmsted County, Minnesota, utilizing the Rochester Epidemiology Project. Arthritis Care and Research, 65(5), 786-792. doi:10.1002/acr.21896. PMCID: PMC3935235.

Vincent A, Brimmer DJ, Whipple MO, Jones JF, Boneva R, Lahr B, Maloney E, St. Sauver J, Reeves WC (2012). Prevalence, incidence and classification of chronic fatigue syndrome in Olmsted County, Minnesota as estimated using the Rochester Epidemiology Project. Mayo Clinic Proceedings, 87(12), 1145-1152. doi:10.1016/j.mayocp.2012.08.015. PMCID: PMC3518652.

Toussaint L, Overvold-Ronningen M, Vincent A, Luedtke C, Whipple MO, Schriever T, Luskin F (2010). Implications of forgiveness enhancement in patients with fibromyalgia and chronic fatigue syndrome. Journal of Health Care Chaplaincy, 16, 123-139. doi:10.1080/08854726.2010.492713.

Whipple MO, Lewis TT, Sutton-Tyrrell K, Matthews KA, Barinas-Mitchell E, Powell LH, Everson-Rose SA (2009). Hopelessness, depressive symptoms and carotid atherosclerosis in women: The Study of Women’s Health Across the Nation (SWAN) Heart Study. Stroke, 40(10), 3166-3172. doi:10.1161/STROKEAHA.109.554519. PMCID: PMC2762349.

Complete List of Published Work in My Bibliography: